The efficiency of vector-valued intensity measures for predicting the seismic demand in gravity dams is investigated.The Soap Folsom gravity dam-reservoir coupled system is selected and numerically analyzed under a set of two-hundred actual ground motions.First, the well-defined scalar IMs are separately investigated, and then they are coupled to f
Contributing to Elimination of Cross-Border Malaria Through a Standardized Solution for Case Surveillance, Data Sharing, and Data Interpretation: Development of a Cross-Border Monitoring System
BackgroundCross-border malaria is a significant obstacle to achieving malaria control and elimination worldwide.ObjectiveThis study aimed to build a cross-border surveillance system that can make MOISTURIZER CONDITIONER comparable and qualified data available to all parties involved in malaria control between French Guiana and Brazil.MethodsData re
Birefringence-derived artifact in optical coherence tomography imaging of the lamina cribrosa in eyes with glaucoma
Abstract We investigated birefringence-derived artifacts that potentially mimic focal defects of the lamina cribrosa (focal LC defects) in optical coherence tomography (OCT) imaging of eyes with glaucoma.This study included 74 eyes of 48 patients Holiday Decorations with glaucoma.Five horizontal line B-scan images of the optic disc were obtained us
Promoting engagement with social fact-checks online: Investigating the roles of social connection and shared partisanship.
Social corrections - where users correct each other - can help rectify inaccurate beliefs.However, social corrections are often ignored.Here we ask under what conditions social corrections promote engagement from corrected users, allowing for greater insight into how users respond to debunking messages (even if such responses are negative).Prior wo
Combination of farnesyl-transferase inhibition with KRAS G12D targeting breaks down therapeutic resistance in pancreatic cancer
Pancreatic adenocarcinoma is one of the deadliest forms of cancer with no effective therapeutic options.A KRAS mutation can be found in up to 90% of all pancreatic tumors, making it a promising therapeutic target.The introduction of new KRAS inhibitors has been a milestone in the history of KRAS mutant tumors; however, therapeutic resistance limits